Medical Laboratory Technologist, Genetics
Company
Sinai Health
About the Diagnostic Medical Genetics teamThe Diagnostic Medical Genetics Laboratory at Mount Sinai Hospital is a hub for cutting-edge diagnostic testing and innovative method and test development. We are dedicated to improving patient care through a deeper understanding of genetics. Equipped with advanced technologies, the lab offers a wide range of genetic and genomic testing, supporting diverse clinical needs across various specialties. A collaborative spirit thrives within the lab, bringing together a team of skilled professionals, including geneticists, genetic counselors, variant analysts, bioinformaticians, medical laboratory technologists and technicians. This team is united by a shared passion for unraveling the complexities of genetic disorders, pioneering new diagnostic and therapeutic approaches, and ultimately, making a tangible difference in the lives of patients and their families.
Location
600 University Ave, Toronto, ON M5G 1X5
Duties
In this role you will:
> Perform Molecular and Cytogenetics procedures as outlined in the laboratory standard operating procedures to aid in diagnosis and management of patients.
> Rotate through the laboratory testing benches, becoming thoroughly familiar with theory and performance of all procedures and techniques relating to each bench area
> Identify and accurately report cytogenetic findings using the International System for Human Cytogenetic Nomenclature
> Ensure the accuracy, legibility and completeness of results submitted for reporting where applicable
> Perform all quality control procedures and basic troubleshooting whenever results are beyond expected or allowable limits according to established protocol
> Accession and process specimens in accordance with Standard Operating Procedures (SOPs)
> Prioritize work and respond to urgent or unpredicted demand for specimen processing or testing
> Prepare reagents, buffers, calibrators, quality control and other materials as required. Assist in inventory control of reagents and supplies
> Perform test/procedures related to method evaluation, test optimization and validation
> Observe and follow the processes, policies and procedures of the quality management system of corresponding discipline(s)
> Assist in orientating and demonstrating procedures or technology to new staff or students as requested
> Perform the following techniques as applicable to the testing being performed and interpret results with an understanding of the disease being analyzed:
>> Next Generation Sequencing (NGS) and Sanger Sequencing, including library preparation and analyses
>> DNA extraction from fresh or frozen blood, fresh, frozen or paraffin-embedded tissue
>> RNA extraction from fresh or frozen blood, fresh or frozen tissue
>> Polymerase Chain Reaction (PCR)
>> Quantitative fluorescent polymerase chain reaction (QF-PCR) techniques and analysis
>> Gel electrophoresis and analysis
>> Microsatellite Instability Testing (MSI) techniques and analysis
>> Multiplex Ligation-dependent Probe Amplification (MLPA) techniques and analysis
>> Microarray techniques and analysis
>> Special stains, FISH and other procedures as required
>>> Microscopic (bright field & fluorescent) analysis of chromosome preparations
>> G-Banding, digital imaging and computer automated karyotyping of chromosome preparations
Requirements
Mandatory:
> Canadian Society for Medical Laboratory Science (CSMLS) certified MLT in Cytogenetics and Molecular Genetics Technology (Dual License)
> Member of the College of Medical Laboratory Technologists of Ontario (CMLTO)
> Candidates eligible to write the upcoming Clinical Genetics CSMLS exam will be considered
Preferred:
> Experience in Medical Genetics
Skills and Knowledge:
> Demonstrated problem recognition and problem solving skills
> Demonstrated organizational, time management and prioritization skills
> Demonstrated satisfactory work performance and attendance record
> In accordance with accreditation standards, employment is conditional upon demonstrating proof of visual colour discrimination ability pertinent to the essential duties of the job
Hours
37.5 hours per week; rotating shifts (days, evenings, nights, weekend) per operational needs
Contact
Name
Talent Acquisition
Telephone
416-586-4800
Job Posting Link
Display Date
2025-03-05
Expiry Date
2025-04-10